PTEN gene inactivation
Showing 1 - 25 of 6,249
Recurrent Glioma, Recurrent Glioblastoma, Poly ADP Ribose Polymerase (PARP) Inhibitor Trial in Hong Kong (Talazoparib)
Recruiting
- Recurrent Glioma
- +4 more
-
Hong Kong, Hong KongDepartment of Clinical Oncology
Aug 19, 2021
Patients With a Constitutional Alteration of the PTEN Gene
Not yet recruiting
- PTEN Gene Mutation
- (no location specified)
Nov 17, 2022
PTEN Gene Mutation, PTEN Hamartoma Tumor Syndrome, PTEN Hamartoma Syndrome Trial in Stanford, Boston, Cleveland (Sirolimus,
Not yet recruiting
- PTEN Gene Mutation
- +2 more
- Sirolimus
- Placebo
-
Stanford, California
- +2 more
Oct 5, 2023
Partial PTEN Deletion in Breast Cancer
Not yet recruiting
- PTEN Gene Deletion
- (no location specified)
Oct 27, 2021
Recurrent Glioblastoma Trial in Zhengzhou (Tislelizumab plus Bevacizumab)
Recruiting
- Recurrent Glioblastoma
- Tislelizumab plus Bevacizumab
-
Zhengzhou, Henan, ChinaHenan Provincial People's Hospital
Sep 11, 2022
PTEN Gene Mutation, PTEN Hamartoma Tumor Syndrome Trial in Palo Alto, Boston, Cleveland (RAD001, Placebo)
Completed
- PTEN Gene Mutation
- PTEN Hamartoma Tumor Syndrome
- RAD001
- Placebo
-
Palo Alto, California
- +2 more
Feb 7, 2022
An Intervention to Increase Genetic Testing in Families Who May
Recruiting
- BRCA1 Mutation
- +21 more
- Intervention Arm At-risk Relative/ARR Contacts
- +5 more
-
Basking Ridge, New Jersey
- +7 more
Nov 22, 2022
CDH1 Germline Mutations in Lobular Breast Cancer
Active, not recruiting
- Lobular Breast Carcinoma
- CDH1 Gene Inactivation
-
Milan, ItalyEuropean Institute of Oncology
Jan 11, 2022
PTEN Gene Mutation, PTEN Hamartoma Tumor Syndrome, PTEN Hamartoma Syndrome Trial in Columbus (Sirolimus)
Recruiting
- PTEN Gene Mutation
- +6 more
-
Columbus, OhioThe Ohio State University Wexner Medical Center
Nov 12, 2021
High Risk Prostate Cancer to Determine Prognosis
Active, not recruiting
- Prostate Cancer
-
Gatineau, Quebec, Canada
- +7 more
Sep 20, 2021
VHL - Von Hippel-Lindau Syndrome, VHL Gene Mutation, VHL Syndrome Trial in Worldwide (Belzutifan)
Active, not recruiting
- VHL - Von Hippel-Lindau Syndrome
- +5 more
-
Bethesda, Maryland
- +10 more
Aug 16, 2022
Coexisting TMPRSS2-ERG Gene Fusion and PTEN Deletion in Prostate
Recruiting
- Prostate Cancer
-
Chicoutimi, Quebec, Canada
- +8 more
Oct 19, 2020
PTEN Expression in Functional and Pathological Endometrial
Completed
- Endometrial Hyperplasia
- Endometrial Adenocarcinoma
- routine stain by H&E.
-
Sohag, EgyptMaisa Hashem Mohammed
Jul 13, 2022
Hepatocellular Carcinoma, Immunotherapy, CAR Trial in Guangzhou (GPC3 and/or TGFß targeting CAR-T cells)
Recruiting
- Hepatocellular Carcinoma
- +5 more
- GPC3 and/or TGFβ targeting CAR-T cells
-
Guangzhou, Guangdong, China
- +1 more
Nov 28, 2020
Metastatic Colon Carcinoma, Metastatic Colorectal Carcinoma, Metastatic Rectal Carcinoma Trial in United States (Laboratory
Active, not recruiting
- Metastatic Colon Carcinoma
- +24 more
- Laboratory Biomarker Analysis
- +2 more
-
Corona, California
- +7 more
Oct 26, 2022
Relation With Low-ovarian Reserve in Endometriomas
Unknown status
- Ovarian Reserve, Endometrioma, PTEN-AKT-FOXO3 Gene Expression
- PTEN-AKT-FOXO3 Gene Expression
-
Bursa, Nilufer, Turkey
- +1 more
Aug 14, 2019
Follow-up Study on Female Carriers With DMD Gene Variants
Not yet recruiting
- Muscular Dystrophy
- +2 more
- No intervention
-
Copenhagen, DenmarkCopenhagen neuromuscular center
Feb 7, 2023
Access to Resources for PTEN Hamartoma Tumor Syndrome
Completed
- PTEN Gene Mutation
-
Tampa, FloridaUniversity of South Florida
Oct 15, 2019
Testicular Cancer Trial in Bratislava (Veliparib, Gemcitabine, Carboplatin)
Completed
- Testicular Cancer
- Veliparib
- +2 more
-
Bratislava, SlovakiaNational Cancer Institute
Mar 2, 2021
High-Risk Prostate Cancer Trial in Portland (Capivasertib, abiraterone acetate)
Not yet recruiting
- High-Risk Prostate Cancer
- Capivasertib
- abiraterone acetate
-
Portland, OregonVA Portland Health Care System, Portland, OR
Jan 17, 2023
Triple Negative Breast Tumors Trial in Worldwide (alpelisib, , nab-paclitaxel)
Active, not recruiting
- Triple Negative Breast Neoplasms
- alpelisib
- +2 more
-
Los Alamitos, California
- +154 more
Jan 12, 2023
PTEN-null Advanced Solid Tumors Trial in New York (Leflunomide)
Not yet recruiting
- PTEN-null Advanced Solid Tumors
-
New York, New YorkIcahn School of Medicine at Mount Sinai
Jul 8, 2022
Idiopathic Infantile Hypercalcemia - Mild Form Trial in Toronto (Rifampin 150 mg, 300 mg capsules and 25 mg/mL oral suspension)
Recruiting
- Idiopathic Infantile Hypercalcemia - Mild Form
- Rifampin 150 mg, 300 mg capsules and 25 mg/mL oral suspension
-
Toronto, Ontario, CanadaThe Hospital for Sick Children
Aug 30, 2021
